PSMB8 Polyclonal Antibody, Alexa Fluor™ 647, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA1972AY-Each-of-1 | In Stock | ₹ 38,003.00 |
PIPA1972AY - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,003.00
GST (18%): ₹ 6,840.54
Total Price: ₹ 44,843.54
Antigen
PSMB8
Classification
Polyclonal
Conjugate
Alexa Fluor 647
Gene
Psmb8
Gene Alias
ALDD; D6S216; D6S216E; DAAP-57C1.3; JMP; large multifunctional protease 7; Lmp7; Lmp-7; low molecular mass polypeptide 7; low molecular mass protein 7; low molecular weight protein 7; macropain subunit C13; Mc13; MC13 (LMP7); MGC1491; multicatalytic endopeptidase complex subunit C13; NKJO; OTTHUMP00000029420; OTTHUMP00000029421; OTTHUMP00000062981; protease component C13; proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteasome (prosome, macropain) subunit, beta type, 8; proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7); proteasome catalytic subunit 3i; proteasome component C13; proteasome subunit beta 5i; proteasome subunit beta 8; proteasome subunit beta type 8; proteasome subunit beta type-8; Proteasome subunit beta-5i; proteasome subunit MC13; proteasome subunit Y2; proteasome-related gene 7; proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteosome beta 8 subunit; PSMB5i; Psmb8; Really interesting new gene 10 protein; Ring10; Y2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5696
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Immunocytochemistry
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.
P28062
Gene Symbols
Psmb8
Immunogen
Synthetic Peptide: C V(259) E S T D V S D L L H Q Y R E A(274)
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1972A647 detects proteasome 20S LMP7 from human cells
- PA1972A647 immunizing peptide corresponds to amino acid residues 259-274 from human proteasome 20S LMP7 protein
- This sequence is completely conserved between human, mouse, rat and sheep
- PA1972A647 immunizing peptide (Cat
- # PEP-132) is available for use in neutralization and control experiments
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure
- The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits
- Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway
- An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides
- This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit
- This gene is located in the class II region of the MHC (major histocompatibility complex)
- Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome
- Proteolytic processing is required to generate a mature subunit
- Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.