PIPA5100126

ATP6V1A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100126-Each-of-1 In Stock ₹ 46,502.50

PIPA5100126 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ATP6V1A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATP6V1A

Gene Alias

70-kDa subunit; AI647066; Atp6a1; Atp6a2; Atp6v1a; Atp6v1a1; ATPase H+ transporting V1 subunit A; ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha 70 kDa, isoform 2; ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; ATPase, H+ transporting, lysosomal V1 subunit A; ATPase, H+ transporting, lysosomal, subunit A1; ATPase, H+ transporting, V1 subunit A, isoform 1; ATPase, H+ transporting, V1 subunit A1; H(+)-transporting two-sector ATPase, subunit A; H+-transporting ATPase chain A, vacuolar (VA68 type); HO68; lysosomal 70kDa; VA68; vacuolar ATP synthase catalytic subunit A, ubiquitous isoform; vacuolar ATPase isoform VA68; vacuolar proton pump alpha subunit 1; vacuolar proton pump subunit alpha; V-ATPase 69 kDa subunit; V-ATPase 69 kDa subunit 1; V-ATPase A subunit 1; V-ATPase subunit A; Vma1; VPP2; V-type proton ATPase catalytic subunit A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11964, 523, 685232

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P38606, P50516

Gene Symbols

ATP6V1A

Immunogen

A synthesized peptide derived from human ATP6V1A(Accession P38606), corresponding to amino acid residues A499-D549.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ATP6V1A
  • ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles
  • V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation
  • V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain
  • The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits
  • The V1 domain contains the ATP catalytic site
  • The V0 domain consists of five different subunits: a, c, c', c&quote, and d
  • Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants
  • This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues
  • Transcript variants derived from alternative polyadenylation exist.