PIPA5100063

D2HGDH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100063-Each-of-1 In Stock ₹ 46,502.50

PIPA5100063 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

D2HGDH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

D2HGDH

Gene Alias

AA408776; AA408778; AI325464; D2HGD; D2HGDH; D2hgdh {ECO:0000250; D-2-hydroxyglutarate dehydrogenase; D-2-hydroxyglutarate dehydrogenase, mitochondrial; FLJ42195; LOW QUALITY PROTEIN: D-2-hydroxyglutarate dehydrogenase, mitochondrial; MGC25181; RGD1307976; UniProtKB:Q8N465}

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

301624, 728294, 98314

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P84850, Q8CIM3, Q8N465

Gene Symbols

D2HGDH

Immunogen

A synthesized peptide derived from human D2HGDH(Accession Q8N465), corresponding to amino acid residues E409-P459.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total D2HGDH
  • This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family
  • This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate
  • Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.