PIPA5100069

Importin 4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100069-Each-of-1 In Stock ₹ 46,502.50

PIPA5100069 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Importin 4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ipo4

Gene Alias

8430408O15Rik; AA409693; Imp4; Imp4a; IMP4B; importin 4; importin 4a; importin-4; Importin-4a; importin-4b; IPO4; Ran-binding protein 4; ranBP4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

290228, 75751, 79711

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8TEX9, Q8VI75

Gene Symbols

Ipo4

Immunogen

A synthesized peptide derived from human IPO4(Accession Q8TEX9), corresponding to amino acid residues L440-N490.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IPO4
  • Importin-4 is a protein that in humans is encoded by the IPO4 gene
  • Functions in nuclear protein import as nuclear transport receptor
  • Serves as receptor for nuclear localization signals (NLS) in cargo substrates
  • Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism
  • At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.