ASAH1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100089-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100089 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ASAH1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ASAH1
Gene Alias
2310081N20Rik; AC; ACDase; acid CDase; acid ceramidase; Acid ceramidase subunit alpha; Acid ceramidase subunit beta; Acylsphingosine deacylase; ASAH; Asah1; HSD33; HSD-33; N-acylethanolamine hydrolase ASAH1; N-acylsphingosine amidohydrolase; N-acylsphingosine amidohydrolase (acid ceramidase) 1; N-acylsphingosine amidohydrolase 1; PHP; PHP32; putative 32 kDa heart protein; SMAPME
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11886, 427, 84431
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q13510, Q6P7S1, Q9WV54
Gene Symbols
ASAH1
Immunogen
A synthesized peptide derived from human ASAH1(Accession Q13510), corresponding to amino acid residues L12-W62.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ASAH1
- ASAH1 encodes a member of the acid ceramidase family of proteins
- Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed
- The processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid
- This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression
- Mutations in this gene have been linked to the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy
- The related pathways include Innate Immune System and Sphingolipid metabolism
- Diseases associated with ASAH1 include Farber Lipogranulomatosis and Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy.