CHMP4B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100092-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100092 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CHMP4B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CHMP4B
Gene Alias
2010012F05Rik; C20orf178; C76846; charged multivesicular body protein 4b; CHMP4A; CHMP4B; chromatin modifying protein 4B; chromatin-modifying protein 4b; CTPP3; CTRCT31; dJ553F4.4; hSnf7-2; hVps32-2; RGD1309846; RGD1565889; Shax1; SNF7; SNF7 homolog associated with Alix 1; Snf7 homologue associated with Alix 1; Snf7-2; Vacuolar protein sorting-associated protein 32-2; vacuolar protein-sorting-associated protein 32-2; Vps32-2; VPS32B
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100359642, 128866, 75608
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9D8B3, Q9H444
Gene Symbols
CHMP4B
Immunogen
A synthesized peptide derived from human CHMP4B(Accession Q9H444), corresponding to amino acid residues M1-E50.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CHMP4B
- CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family
- The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes
- The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1
- The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway
- The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding
- These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.