PIPA5100098

HERPUD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100098-Each-of-1 In Stock ₹ 46,502.50

PIPA5100098 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

HERPUD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HERPUD1

Gene Alias

Herp; HERPUD1; homocysteine inducible ER protein with ubiquitin like domain 1; homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; KIAA0025; Methyl methanesulfonate (MMF)-inducible fragment protein 1; Mif1; Mifl; MMS-inducible; Sup

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9709

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15011

Gene Symbols

HERPUD1

Immunogen

A synthesized peptide derived from human HERPUD1(Accession Q15011), corresponding to amino acid residues M1-P46.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total HERP
  • The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response
  • This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system
  • This gene may play a role in both UPR and ERAD
  • Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system
  • This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression
  • Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms
  • The full-length nature of all transcript variants has not been determined.