PIPA5100150

INSIG1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100150-Each-of-1 In Stock ₹ 45,345.50

PIPA5100150 - Each of 1

₹ 45,345.50

In Stock

Quantity

1

Base Price: ₹ 45,345.50

GST (18%): ₹ 8,162.19

Total Price: ₹ 53,507.69

Antigen

INSIG1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

INSIG1

Gene Alias

1810013C12Rik; CL6; CL-6; fb55a03; fi35b10; growth response protein (CL-6); immediate-early protein CL-6; INSIG1; INSIG-1; INSIG-1 membrane protein; insulin induced gene 1; insulin induced protein 1; insulin-induced gene 1 protein; Insulin-induced growth response protein CL-6; MGC1405; wu:fb55a03; wu:fi35b10; zgc:55439

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

231070, 3638

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O15503, Q8BGI3

Gene Symbols

INSIG1

Immunogen

A synthesized peptide derived from human INSIG1(Accession O15503), corresponding to amino acid residues W127-A177.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total INSIG1
  • Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway
  • This gene is an insulin-induced gene
  • It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells
  • This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.