PIPA5100287
Nebulin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100287-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100287 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Nebulin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NEB
Gene Alias
AI595938; DKFZp686C1456; FLJ11505; FLJ36536; FLJ39568; FLJ39584; NEB; NEB177D; nebulin; NEM2; nemaline myopathy type 2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17996, 311029, 4703
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P20929
Gene Symbols
NEB
Immunogen
A synthesized peptide derived from human NEB(Accession P20929), corresponding to amino acid residues Y5906-T5956.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The immunogen sequence for PA5-100287 is KESQQMQSGK EYRKD
- Antibody detects endogenous levels of total NEB
- This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle
- In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein
- The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules
- Protein isoform sizes vary from 600 to 800 kDa due to alternative splicing that is tissue-, species-, and developmental stage-specific
- Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript
- Mutations in this gene are associated with recessive nemaline myopathy.