PIPA5100881

NFE2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100881-Each-of-1 In Stock ₹ 46,502.50

PIPA5100881 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

NFE2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NFE2

Gene Alias

leucine zipper protein NF-E2; NFE2; NF-E2; NF-E2/P45; nuclear factor (erythroid-derived 2), 45kD; nuclear factor (erythroid-derived 2), 45kDa; nuclear factor, erythroid 2; nuclear factor, erythroid derived 2; nuclear factor, erythroid-derived 2 45 kDa subunit; p45; p45 NF-E2; p45NFE2; p45nf-e2; Transcription factor NF-E2 45 kDa subunit

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18022, 366998, 4778

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q07279, Q16621, Q6AYT2

Gene Symbols

NFE2

Immunogen

A synthesized peptide derived from human NFE2(Accession Q16621), corresponding to amino acid residues R272-M322.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NFE2
  • Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation
  • Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR)
  • This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters
  • Requires MAFK or other small MAF proteins for binding to the NF-E2 motif
  • May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.