NUP160 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101723-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5101723 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NUP160
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NUP160
Gene Alias
160 kDa nucleoporin; 160kDa; 2810011M03Rik; AA414952; AU020188; Gene trap locus 1-13 protein; gene trap locus-13; Gtl1-13; Gtl13; GTL-13; KIAA0197; mKIAA0197; Nuclear pore complex protein Nup160; nucleoporin 160; nucleoporin 160kD; nucleoporin 160kDa; nucleoporin Nup160; NUP120; Nup160
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23279, 59015
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q12769, Q9Z0W3
Gene Symbols
NUP160
Immunogen
A synthesized peptide derived from human NUP160(Accession Q12769), corresponding to amino acid residues E425-A475.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total NUP160
- The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm
- The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p
- While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20
- Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions
- NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment
- Multiple isoforms of NUP160 are known to exist.