PIPA5101355

MRPL18 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101355-Each-of-1 In Stock ₹ 46,502.50

PIPA5101355 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MRPL18

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mrpl18

Gene Alias

1010001C05Rik; 39S ribosomal protein L18, mitochondrial; C79879; HSPC071; L18mt; Mitochondrial large ribosomal subunit protein uL18m; mitochondrial ribosomal protein L18; Mrpl18; MRP-L18

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29074, 67681

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9CQL5, Q9H0U6

Gene Symbols

Mrpl18

Immunogen

A synthesized peptide derived from human MRPL18(Accession Q9H0U6), corresponding to amino acid residues L24-S74.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MRPL18
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion
  • Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit
  • They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed
  • Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA
  • Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology
  • This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family
  • Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.