PIPA5104453
Involucrin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104453-Each-of-1 | In Stock | ₹ 45,345.50 |
PIPA5104453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,345.50
GST (18%): ₹ 8,162.19
Total Price: ₹ 53,507.69
Antigen
Involucrin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IVL
Gene Alias
1110019C06Rik; involucrin; IVL
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16447, 3713
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P07476, P48997
Gene Symbols
IVL
Immunogen
A synthesized peptide derived from human IVL(Accession P07476), corresponding to amino acid residues A548-K585.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total Involucrin
- Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase
- Involucrin is expressed in a range of stratified squamous epithelia, including the cornea
- In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer
- Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions and is reduced in severe dysplasias of the larynx and cervix
- Its gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.