PIPA5101705
NRL Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101705-Each-of-1 | In Stock | ₹ 47,837.50 |
PIPA5101705 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,837.50
GST (18%): ₹ 8,610.75
Total Price: ₹ 56,448.25
Antigen
NRL
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NRL
Gene Alias
D14H14S46E; D14S46E; neural retina leucine zipper; neural retina leucine zipper gene; neural retinal-specific leucine zipper; neural retina-specific leucine zipper protein; Nrl; NRL-MAF; RP27
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18185, 4901
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P54845, P54846
Gene Symbols
NRL
Immunogen
A synthesized peptide derived from human NRL(Accession P54845), corresponding to amino acid residues M1-P49.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total NRL
- Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, which characteristically contain a highly conserved basic leucine zipper (bZIP)-DNA binding motif
- Both Nrl and c-Maf preferentially bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles
- The Maf-Nrl subfamily regulates the expression of cell type-specific genes in tissues of the hematopoietic system, cerebellum and developing hindbrain
- Maf and Nrl proteins bind an extended AP-1-like sequence and can form heterodimers with Fos and Jun transcription factors
- In retinal cells and photoreceptor cells, Nrl promotes the expression of rhodopsin through binding to the Nrl response element present in the rhodopsin promoter
- Nrl is expressed throughout the developing central and peripheral nervous system during neuronal differentiation, and its expression is restricted to neocortex, brainstem and retinal neurons during adulthood.