PIPA5101961
ZC3H13 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101961-Each-of-1 | In Stock | ₹ 45,345.50 |
PIPA5101961 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,345.50
GST (18%): ₹ 8,162.19
Total Price: ₹ 53,507.69
Antigen
ZC3H13
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZC3H13
Gene Alias
2600010B19Rik; 3110050K21Rik; 4930570G11Rik; C87618; KIAA0853; RGD1307729; ZC3H13; Zinc finger CCCH domain-containing protein 13; zinc finger CCCH type containing 13; zinc finger CCCH-type containing 13
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23091, 67302
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
E9Q784, Q5T200
Gene Symbols
ZC3H13
Immunogen
A synthesized peptide derived from human ZC3H13(Accession Q5T200), corresponding to amino acid residues R1577-N1627.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ZC3H13
- The zinc finger CCCH domain-containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1-type zinc finger
- ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR
- Two isoforms of ZC3H13 exists as a result of alternative splicing events
- The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes
- Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene
- As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival
- Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.