PIPA5102396

Cystatin 8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102396-Each-of-1 In Stock ₹ 46,502.50

PIPA5102396 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Cystatin 8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CST8

Gene Alias

CRES; CST 8; CST8; Cst-rs1; CTES5; cystatin 8; cystatin 8 (cystatin-related epididymal specific); cystatin 8 (cystatin-related epididymal spermatogenic); cystatin-8; Cystatin-related epididymal spermatogenic protein; cystatin-related epididymal-specific protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10047, 13012, 29679

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60676, O88969, P32766

Gene Symbols

CST8

Immunogen

A synthesized peptide derived from human CST8(Accession O60676), corresponding to amino acid residues L81-E131.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CST8
  • The cystatin superfamily is a well-established family of cysteine protease inhibitors
  • All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes
  • The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily
  • CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases
  • They are also preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs
  • Therefore, CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems
  • As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein that is expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.