PIPA5102441

IL23R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102441-Each-of-1 In Stock ₹ 45,345.50

PIPA5102441 - Each of 1

₹ 45,345.50

In Stock

Quantity

1

Base Price: ₹ 45,345.50

GST (18%): ₹ 8,162.19

Total Price: ₹ 53,507.69

Antigen

IL23R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il23r

Gene Alias

IBD17; IL 23R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

149233, 209590, 689932

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q5VWK5, Q8K4B4

Gene Symbols

Il23r

Immunogen

A synthesized peptide derived from human IL23R(Accession Q5VWK5), corresponding to amino acid residues T40-K90.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IL23R
  • IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling
  • Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner
  • Alternative splicing results in six spliced isoforms of IL-23R
  • Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.