PIPA5102445

KPNA2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102445-Each-of-1 In Stock ₹ 46,502.50

PIPA5102445 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KPNA2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KPNA2

Gene Alias

2410044B12Rik; IMA2; importin; importin alpha 2; importin alpha P1; Importin subunit alpha-1; importin subunit alpha-2; importin-alpha-P1; IPOA 1; IPOA1; IPOA1 QIP2; karyopherin (importin) alpha 2; Karyopherin A2; karyopherin alpha 2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); karyopherin subunit alpha 2; karyopherin subunit alpha-2; Kpna2; m-importin-alpha-P1; nuclear import protein; pendulin; Pore targeting complex 58 kDa subunit; PTAC58; QIP2; RAG cohort 1; RAG cohort protein 1; RCH 1; RCH1; SRP 1; SRP1; SRP1 alpha; SRP1alpha; SRP1-alpha

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16647, 3838, 85245

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P52292, P52293

Gene Symbols

KPNA2

Immunogen

A synthesized peptide derived from human KPNA2(Accession P52292), corresponding to amino acid residues D44-L94.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total KPNA2
  • The import of proteins into the nucleus is a process that involves at least 2 steps
  • The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex
  • Imported proteins require a nuclear localization sequence which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart
  • Proteins involved in the first step of nuclear import have been identified in different systems
  • These include the Xenopus protein importin and its yeast homolog, SRP1, which bind to the NLS
  • KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins
  • KPNA2 also may play a role in VJ recombination.