PIPA5102370

alpha Actinin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102370-Each-of-1 In Stock ₹ 45,345.50

PIPA5102370 - Each of 1

₹ 45,345.50

In Stock

Quantity

1

Base Price: ₹ 45,345.50

GST (18%): ₹ 8,162.19

Total Price: ₹ 53,507.69

Antigen

alpha Actinin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ACTN1

Gene Alias

3110023F10Rik; actinin; actinin 1 smooth muscle; actinin alpha 1; actinin, alpha 1; Actn1; Actn1a; alpha actinin 1a; alpha-actinin; alpha-actinin cytoskeletal isoform; Alpha-actinin-1; BDPLT15; F-actin cross-linking protein; fibroblast alpha actinin; FLJ40884; FLJ54432; hypothetical protein; hypothetical protein LOC524770; I79_004057; non-muscle alpha-actinin 1; non-muscle alpha-actinin-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

109711, 81634, 87

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P12814, Q7TPR4, Q9Z1P2

Gene Symbols

ACTN1

Immunogen

A synthesized peptide derived from human ACTN1(Accession P12814), corresponding to amino acid residues K31-E81.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total alpha-Actinin
  • Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins
  • Alpha actinin is an actin-binding protein with multiple roles in different cell types
  • In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane
  • In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments
  • This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene
  • Three transcript variants encoding different isoforms have been found for this gene.