PIPA5102893
IRG1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102893-Each-of-1 | In Stock | ₹ 45,078.50 |
PIPA5102893 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,078.50
GST (18%): ₹ 8,114.13
Total Price: ₹ 53,192.63
Antigen
IRG1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACOD1
Gene Alias
ACOD1; Aconitate decarboxylase; aconitate decarboxylase 1; CAD; Cis-aconitate decarboxylase; cis-aconitic acid decarboxylase; Immune-responsive gene 1 protein; immune-responsive gene 1 protein homolog; immunoresponsive 1 homolog; IRG1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
730249
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
A6NK06
Gene Symbols
ACOD1
Immunogen
A synthesized peptide derived from human ACOD1(Accession A6NK06), corresponding to amino acid residues I439-S481.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total IRG1
- Involved in the inhibition of the inflammatory response
- Acts as a negative regulator of the Toll-like receptors (TLRs)- mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages
- Involved in antimicrobial response of innate immune cells; IRG1- mediated itaconic acid production contributes to the antimicrobial activity of macrophages
- Plays a role in the embryo implantation.