PIPA5102948

CD72 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102948-Each-of-1 In Stock ₹ 46,502.50

PIPA5102948 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CD72

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD72

Gene Alias

B-cell differentiation antigen CD72; CD72; CD72 antigen; Cd72 molecule; CD72b; CD72c; Ly-19; Ly32; Ly-32; LYB2; Lyb-2; Ly-m19; lymphocyte antigen 32; RP11-331F9.9

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12517, 971

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P21854, P21855

Gene Symbols

CD72

Immunogen

A synthesized peptide derived from human CD72(Accession P21854), corresponding to amino acid residues R176-C226.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CD72
  • CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages
  • Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness
  • Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.