PIPA5102968
CAB39 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102968-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5102968 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CAB39
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CAB39
Gene Alias
AA408805; AA960512; C78372; Cab39; calcium binding protein 39; calcium binding protein, 39 kDa; calcium-binding protein 39; CGI-66; MO25; MO25alpha; Protein Mo25
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12283, 51719
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q06138, Q9Y376
Gene Symbols
CAB39
Immunogen
A synthesized peptide derived from human CAB39(Accession Q9Y376), corresponding to amino acid residues Q289-Q339.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CAB39
- Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer
- The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS
- LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha)
- STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1
- The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).