PIPA5102992

TRIP10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102992-Each-of-1 In Stock ₹ 46,502.50

PIPA5102992 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TRIP10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Trip10

Gene Alias

AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

106628, 116717, 9322

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P97531, Q15642, Q8CJ53

Gene Symbols

Trip10

Immunogen

A synthesized peptide derived from human TRIP10(Accession Q15642), corresponding to amino acid residues S296-P346.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TRIP10
  • Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling
  • Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis
  • Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules
  • Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex
  • Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles
  • Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells
  • May be required for the lysosomal retention of FASLG/FASL.