PIPA5103025

UGGT1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103025-Each-of-1 In Stock ₹ 46,502.50

PIPA5103025 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

UGGT1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Uggt1

Gene Alias

0910001L17Rik; A930007H10Rik; AA589501; AI414429; AI448372; C820010P03Rik; Gt; HUGT1; RUGT; rUGT1; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose glycoprotein glucosyltransferase 1; UDP-glucose glycoprotein: glucosyltransferase UGGT; UDP-glucose:glycoprotein glucosyltransferase; UDP-glucose:glycoprotein glucosyltransferase 1; UGCGL1; Uggt; Uggt1; Ugt1; Ugtr

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56886

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9NYU2

Gene Symbols

Uggt1

Immunogen

A synthesized peptide derived from human UGGT1(Accession Q9NYU2), corresponding to amino acid residues E160-F210.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total UGGT1
  • UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides
  • UGGT catalyzes the transfer of glucose from UDP-glucose to Man7-9GlcNAc2-moiety of unfolded glycoproteins in a Ca2+ dependent reaction
  • UGGT binds unfolded glycoprotein via two elements on its substrate: a N-acetylglucosamine unit on the oligosaccharide and hydrophobic amino acids that are exposed in the denatured conformation
  • It is postulated that UGGT serves as a sensor that is able to distinguish between folded and denatured protein in the ER.