TRAM2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103036-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TRAM2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRAM2
Gene Alias
C330003D03Rik; KIAA0057; LOC100361830; tram2; TRAM-like protein; Translocating chain-associated membrane protein 2; translocating chain-associating membrane protein 2; translocation associated membrane protein 2; wu:fb20c11; wu:fi23a12; zgc:111902; zgc:55869; zgc:76937
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100361830, 170829, 9697
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q15035, Q924Z5
Gene Symbols
TRAM2
Immunogen
A synthesized peptide derived from human TRAM2(Accession Q15035), corresponding to amino acid residues R340-P370.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total TRAM2
- Necessary for collagen type I synthesis
- May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon
- This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding
- Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).