PIPA5103183

AMID Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103183-Each-of-1 In Stock ₹ 46,502.50

PIPA5103183 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

AMID

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AIFM2

Gene Alias

5430437E11Rik; AIFM2; Amid; apoptosis inducing factor, mitochondria associated 2; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; D730001I10Rik; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; PRG3; RP11-367H5.2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

361843, 71361, 84883

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8BUE4, Q9BRQ8

Gene Symbols

AIFM2

Immunogen

A synthesized peptide derived from human AIFM2(Accession Q9BRQ8), corresponding to amino acid residues M91-R141.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total AIFM2
  • The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses
  • PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells
  • PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF
  • Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis
  • The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.