PIPA5103211

Laminin beta-2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103211-Each-of-1 In Stock ₹ 46,502.50

PIPA5103211 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Laminin beta-2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LAMB2

Gene Alias

AW211941, Lamb2, Lamb-2, Laminin B1s chain, laminin chain B3, laminin chain beta 2, Laminin S, laminin subunit beta 2, laminin subunit beta-2, laminin, beta 2, laminin, beta 2 (laminin S), laminin-11 subunit beta, Laminin-14 subunit beta, laminin-15 subunit beta, Laminin-3 subunit beta, laminin-4 subunit beta, Laminin-7 subunit beta, laminin-9 subunit beta, LAMS, NPHS5, npht, SLAM, S-LAM beta, S-laminin subunit beta

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16779, 25473, 3913

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P15800, P55268, Q61292

Gene Symbols

LAMB2

Immunogen

A synthesized peptide derived from human LAMB2(Accession P55268), corresponding to amino acid residues G72-A122.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total LAMB2
  • Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane
  • Two main subtypes of nuclear lamins can be distinguished, i.e
  • A-type lamins and B-type lamins
  • The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e
  • lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e
  • lamin B1 and lamin B2
  • Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy
  • In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.