PIPA5103220

NOX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103220-Each-of-1 In Stock ₹ 46,858.50

PIPA5103220 - Each of 1

₹ 46,858.50

In Stock

Quantity

1

Base Price: ₹ 46,858.50

GST (18%): ₹ 8,434.53

Total Price: ₹ 55,293.03

Antigen

NOX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Nox1

Gene Alias

GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114243, 237038, 27035

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8CIZ9, Q9WV87, Q9Y5S8

Gene Symbols

Nox1

Immunogen

A synthesized peptide derived from human NOX1(Accession Q9Y5S8), corresponding to amino acid residues R471-H521.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NOX1
  • Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress
  • NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox
  • Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv
  • NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc
  • NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain
  • NOX1 have the potential to be effective treatments for a range of ischemic diseases.