ITFG2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103447-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103447 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ITFG2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITFG2
Gene Alias
2700050P07Rik; AI646725; integrin alpha FG-GAP repeat containing 2; integrin-alpha FG-GAP repeat-containing protein 2; integrin-alpha FG-GAP repeat-containing protein 2; KICSTOR complex protein ITFG2; ITFG2; KICSTOR complex protein ITFG2; MDS028; RGD1311944
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
101142, 55846
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q91WI7, Q969R8
Gene Symbols
ITFG2
Immunogen
A synthesized peptide derived from human ITFG2(Accession Q969R8), corresponding to amino acid residues L198-R248.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ITFG2
- As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway
- Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases
- Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids
- In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated
- The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.