CNGB3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103768-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103768 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CNGB3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CNGB3
Gene Alias
ACHM1; cng channel; CNG channel beta-3; CNGB3; cone photoreceptor cGMP-gated cation channel beta-subunit; Cone photoreceptor cGMP-gated channel subunit beta; cyclic nucleotide gated channel beta 3; cyclic nucleotide-gated cation channel beta-3; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
30952, 54714
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9JJZ9, Q9NQW8
Gene Symbols
CNGB3
Immunogen
A synthesized peptide derived from human CNGB3(Accession Q9NQW8), corresponding to amino acid residues N90-R140.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CNGB3
- Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger
- This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors
- Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3
- Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.