HOXD11 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103895-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103895 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
HOXD11
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HOXD11
Gene Alias
E230017H14Rik, homeo box 4F, homeo box D11, homeobox D11, homeobox protein Hox-4.6, Homeobox protein Hox-4F, homeobox protein Hox-5.5, Homeobox protein Hox-D11, HOX11, HOX4, Hox-4.6, Hox-4.6, mouse, homolog of, HOX4F, Hox-5.4, Hox-5.5, Hoxd11, Hoxd-11, LOC102553842, uncharacterized LOC102553842
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
102553842, 15431, 3237
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P23813, P31277
Gene Symbols
HOXD11
Immunogen
A synthesized peptide derived from human HOXD11(Accession P31277), corresponding to amino acid residues G206-K256.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total HOXD11
- HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region
- It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus
- HOX11 is required for maintenance of the developing spleen and cell survival
- The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus
- It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator
- The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35;q24) or t(10:14)(q24;qll) translocation
- The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes
- HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.