ARHGAP24 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104104-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104104 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ARHGAP24
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARHGAP24
Gene Alias
0610025G21Rik; Arhgap24; Down-regulated in nephrectomized rat kidney #2; DR-NR#2; Filamin-A-associated RhoGAP; FILGAP; p73; p73RhoGAP; RAC1- and CDC42-specific GTPase-activating protein of 72 kDa; RCGAP72; RC-GAP72; Rho GTPase activating protein 24; rho GTPase-activating protein 24; rhoGAP of 73 kDa; Rho-type GTPase-activating protein 24; Sarcoma antigen NY-SAR-88; si:ch211-65i12.2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
231532, 305156, 83478
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q5U2Z7, Q8C4V1, Q8N264
Gene Symbols
ARHGAP24
Immunogen
A synthesized peptide derived from human ARHGAP24(Accession Q8N264), corresponding to amino acid residues S573-A623.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total RHG24
- Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization
- Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state
- Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity
- Able to suppress RAC1 and CDC42 activity in vitro
- Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia
- Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.