BCCIP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104425-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104425 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BCCIP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BCCIP
Gene Alias
1110013J05Rik; Bccip; BCCIPalpha; BCCIPbeta; BRCA2 and CDKN1A interacting protein; BRCA2 and CDKN1A-interacting protein; BRCA2 and Cip1/p21 interacting protein; cdk inhibitor p21 binding protein; p21- and CDK-associated protein 1; Protein TOK-1; TOK1; TOK-1; TOK-1alpha; TOK-1beta
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56647
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9P287
Gene Symbols
BCCIP
Immunogen
A synthesized peptide derived from human BCCIP(Accession Q9P287), corresponding to amino acid residues F256-D306.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total BCCIP
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins
- It is an evolutionarily conserved nuclear protein with multiple interacting domains
- The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium
- Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21
- This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression
- Multiple transcript variants encoding different isoforms have been described for this gene.