PIPA5104451

Factor VIII Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104451-Each-of-1 In Stock ₹ 47,125.50

PIPA5104451 - Each of 1

₹ 47,125.50

In Stock

Quantity

1

Base Price: ₹ 47,125.50

GST (18%): ₹ 8,482.59

Total Price: ₹ 55,608.09

Antigen

Factor VIII

Classification

Polyclonal

Conjugate

Unconjugated

Gene

F8

Gene Alias

AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14069, 2157

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P00451, Q06194

Gene Symbols

F8

Immunogen

A synthesized peptide derived from human F8(Accession P00451), corresponding to amino acid residues H2174-P2224.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Factor VIII
  • This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa
  • This gene produces two alternatively spliced transcripts
  • Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex
  • This protein undergoes multiple cleavage events
  • Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc
  • This binding domain is essential for coagulant activity
  • Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.