Phospho-mTOR (Thr2446) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104899-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104899 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-mTOR (Thr2446)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MTOR
Gene Alias
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2475, 56717, 56718
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P42345, P42346, Q9JLN9
Gene Symbols
MTOR
Immunogen
A synthesized peptide derived from human MTOR(Accession P42345), corresponding to amino acid residues around phosphorylated Thr2446.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of mTOR only when phosphorylated at Threonine 2446
- FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation
- Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer
- FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics
- Mutations affecting the gene results in Smith-Kingsmore syndrome.