Phospho-SKP1 (Thr131) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105306-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105306 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-SKP1 (Thr131)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SKP1
Gene Alias
15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated p19; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; MGC34403; OCP2; OCP-2; OCP-II; OCP-II protein; organ of Corti protein 2; Organ of Corti protein II; p19A; p19Skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; RNA polymerase II elongation factor-like protein OCP2; SIII; Skp1; Skp1a; S-phase kinase-associated protein 1; S-phase kinase-associated protein 1A; TCEB1L; transcription elongation factor B polypeptide 1-like
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21402, 287280, 6500
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P63208, Q6PEC4, Q9WTX5
Gene Symbols
SKP1, Skp1a
Immunogen
A synthesized peptide derived from human SKP1(Accession P63208), corresponding to amino acid residues around phosphorylated Thr131.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Skp1 only when phosphorylated at Thr131
- This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins
- This protein binds directly to the F-box motif found in F-box proteins
- SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteasome
- Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development
- Studies have also characterized the protein as an RNA polymerase II elongation factor
- Alternative splicing of this gene results in two transcript variants
- A related pseudogene has been identified on chromosome 7.