Phospho-IL10RA (Tyr496) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104991-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104991 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-IL10RA (Tyr496)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Il10ra
Gene Alias
AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3587
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q13651
Gene Symbols
Il10ra
Immunogen
A synthesized peptide derived from human IL10RA(Accession Q13651), corresponding to amino acid residues around phosphorylated Tyr496.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of IL-10R alpha only when phosphorylated at Tyrosine 496
- The protein encoded by this gene is a receptor for interleukin 10
- This protein is structurally related to interferon receptors
- It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines
- This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway
- Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases
- Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.