PIPA5109852

IL10RA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109852-Each-of-1 In Stock ₹ 48,193.50

PIPA5109852 - Each of 1

₹ 48,193.50

In Stock

Quantity

1

Base Price: ₹ 48,193.50

GST (18%): ₹ 8,674.83

Total Price: ₹ 56,868.33

Antigen

IL10RA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il10ra

Gene Alias

AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

117539, 16154, 3587

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.88 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

Q13651, Q61727

Gene Symbols

Il10ra

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 265-410 of human IL10RA (NP_0015492)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: KLPSVLLFKK PSPFIFISQR PSPETQDTIH PLDEEAFLKV SPELKNLDLH GSTDSGFGST KPSLQTEEPQ FLLPDPHPQA DRTLGNREPP VLGDSCSSGS SNSTDSGICL QEPSLSPSTG PTWEQQVGSN SRGQDDSGID LVQNSE The protein encoded by this gene is a receptor for interleukin 10
  • This protein is structurally related to interferon receptors
  • It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines
  • This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway
  • Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases
  • Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.