Phospho-SMAD1 (Ser187) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105003-Each-of-1 | In Stock | ₹ 41,518.50 |
PIPA5105003 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,518.50
GST (18%): ₹ 7,473.33
Total Price: ₹ 48,991.83
Antigen
Phospho-SMAD1 (Ser187)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD1
Gene Alias
AI528653, BSP1, BSP-1, dwarfin-A, Dwf-A, DWFC, hSMAD1, JV41, JV4-1, JV5-1, MAD (mothers against decapentaplegic, Drosophila) homolog 1, MAD homolog 1, MAD homolog1 (mothers against decapentaplegic, Drosophila), MAD, mothers against decapentaplegic homolog 1, Madh1, MADH5, MADR1, Mad-related protein 1, Mlp1, mMad1, mothers against decapentaplegic homolog 1, mothers against DPP homolog 1, mothers-against-DPP-related 1, Mothers-against-DPP-related-1, MusMLP, OTTHUMP00000220456, SMAD, Smad 1, SMAD family member 1, SMAD, mothers against DPP homolog 1, Smad1, SMAD5, TGF-beta signaling protein 1, transforming growth factor-beta signaling protein 1, Transforming growth factor-beta-signaling protein 1
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17125, 4086
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P70340, Q15797
Gene Symbols
SMAD1
Immunogen
A synthesized peptide derived from human SMAD1(Accession Q15797), corresponding to amino acid residues around phosphorylated Ser187.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Smad1 only when phosphorylated at Serine 187
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C
- elegans gene Sma
- SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways
- This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses
- In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase
- The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation
- This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation
- Alternatively spliced transcript variants encoding the same protein have been observed.