Phospho-LKB1 (Thr189) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105005-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105005 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-LKB1 (Thr189)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STK11
Gene Alias
AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20869, 6794
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q15831, Q9WTK7
Gene Symbols
STK11
Immunogen
A synthesized peptide derived from human STK11(Accession Q15831), corresponding to amino acid residues around phosphorylated Thr189.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of LKB1 only when phosphorylated at Threonine 189
- LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor
- LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways
- LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis
- LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK
- Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.