PIPA5105082

Phospho-PPAR delta (Thr256) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105082-Each-of-1 In Stock ₹ 46,502.50

PIPA5105082 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-PPAR delta (Thr256)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ppard

Gene Alias

FAAR; MGC3931; Nr1c2; NUC1; NUC-1; NUCI; NUCII; nuclear hormone receptor; nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; OTTHUMP00000016256; OTTHUMP00000016257; peroxisome proliferative activated receptor delta; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor beta; peroxisome proliferator activated receptor delta; peroxisome proliferator activator receptor beta; peroxisome proliferator activator receptor delta; peroxisome proliferator activator receptor, delta; peroxisome proliferator-activated nuclear receptor beta/delta variant 2; Peroxisome proliferator-activated receptor beta; Peroxisome proliferator-activated receptor delta; PPAR[b]; PPARB; Pparb/d; PPARbeta; PPAR-beta; Ppard; PPARdelta; PPAR-delta; PPARdelta/beta

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19015, 25682, 397297, 5467

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P35396, Q03181

Gene Symbols

Ppard

Immunogen

A synthesized peptide derived from human PPARD(Accession Q03181), corresponding to amino acid residues around phosphorylated Thr256.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of PPARD only when phosphorylated at Thr256
  • This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family
  • PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells
  • PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer
  • This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma
  • It may function as an integrator of transcription repression and nuclear receptor signaling
  • The expression of this gene is found to be elevated in colorectal cancer cells
  • The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway
  • Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.