Phospho-GLI2 (Ser234) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105347-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105347 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-GLI2 (Ser234)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GLI2
Gene Alias
AW546128; CJS; GLI family zinc finger 2; GLI family zinc finger protein 2; GLI2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9; oncogene GLI2; PHS2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Thp; THP1; THP2; zinc finger protein GLI2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2736
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P10070
Gene Symbols
GLI2
Immunogen
A synthesized peptide derived from human GLI2(Accession P10070), corresponding to amino acid residues around phosphorylated Ser234.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Gli2 only when phosphorylated at Ser234
- Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family
- Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs
- These motifs contain conserved H-C links
- Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell
- The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression
- It is also thought to play a role during embryogenesis
- The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.