PIPA5105241

Phospho-GAB2 (Ser159) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105241-Each-of-1 In Stock ₹ 46,502.50

PIPA5105241 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-GAB2 (Ser159)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GAB2

Gene Alias

AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14389, 84477, 9846

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9EQH1, Q9UQC2, Q9Z1S8

Gene Symbols

GAB2

Immunogen

A synthesized peptide derived from human GAB2(Accession Q9UQC2), corresponding to amino acid residues around phosphorylated Ser159.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Gab2 only when phosphorylated at Ser159
  • This gene is a member of the GRB2-associated binding protein (GAB) gene family
  • These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein
  • They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors
  • The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor
  • Two alternatively spliced transcripts encoding different isoforms have been described for this gene.