PIPA5105577

Phospho-MAPKAPK2 (Thr221, Thr222) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105577-Each-of-1 In Stock ₹ 46,502.50

PIPA5105577 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-MAPKAPK2 (Thr221, Thr222)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPKAPK2

Gene Alias

AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17164, 289014, 9261

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P49137, P49138

Gene Symbols

MAPKAPK2

Immunogen

A synthesized peptide derived from human MAPKAPK2(Accession P49137), corresponding to amino acid residues around phosphorylated Thr221.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of MAPKAPK2 only when phosphorylated at Thr221/222
  • MAPKAPK2 mediates p38 and ERK signaling in vivo
  • It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation
  • MAPKAPK2 encodes a member of the Ser/Thr protein kinase family
  • MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase
  • In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation
  • Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo
  • Two transcript variants encoding two different isoforms have been found for MAPKAPK2.