Phospho-MAPKAPK2 (Thr334) Recombinant Rabbit Monoclonal Antibody (MAPKAPK2T334-H2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537010-Each-of-1 | In Stock | ₹ 33,019.00 |
PIMA537010 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,019.00
GST (18%): ₹ 5,943.42
Total Price: ₹ 38,962.42
Antigen
Phospho-MAPKAPK2 (Thr334)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P49137, P49138
Gene Symbols
MAPKAPK2
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Thr334 of human phospho MAPKAPK-2.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG κ
Applications
Flow Cytometry, Western Blot
Clone
MAPKAPK2T334-H2
Conjugate
Unconjugated
Gene
MAPKAPK2
Gene Alias
AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
17164, 9261
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- MAPKAPK2 mediates p38 and ERK signaling in vivo
- It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation
- MAPKAPK2 encodes a member of the Ser/Thr protein kinase family
- MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase
- In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation
- Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo
- Two transcript variants encoding two different isoforms have been found for MAPKAPK2.