PIPA5105823

Phospho-p300 (Ser1834) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105823-Each-of-1 In Stock ₹ 46,502.50

PIPA5105823 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-p300 (Ser1834)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EP300

Gene Alias

A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170915, 2033, 328572

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

B2RWS6, Q09472

Gene Symbols

EP300

Immunogen

A synthesized peptide derived from human EP300(Accession Q09472), corresponding to amino acid residues around phosphorylated Ser1834.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of KAT3B / p300 only when phosphorylated at Ser1834
  • EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein
  • p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB
  • This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A
  • EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.