Phospho-FANCD2 (Thr691) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106175-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5106175 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-FANCD2 (Thr691)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FANCD2
Gene Alias
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
211651, 2177
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q80V62, Q9BXW9
Gene Symbols
FANCD2
Immunogen
A synthesized peptide derived from human FANCD2(Accession Q9BXW9), corresponding to amino acid residues around phosphorylated Thr691.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of FANCD2 only when phosphorylated at Thr691
- FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability
- It promotes accurate and efficient pairing of homologs during meiosis
- FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing
- It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress
- FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin
- Defects in the FANCD2 gene result in Fanconi anemia complementation group D2
- This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.