CTNNA3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106401-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5106401 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CTNNA3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CTNNA3
Gene Alias
4930429L08Rik; 4933408A16; Alpha T-catenin; Alpha-3 catenin; alpha-catenin-like protein; alpha-T-catenin; ARVD13; Cadherin-associated protein; catenin (cadherin associated protein), alpha 3; catenin (cadherin-associated protein), alpha 3; catenin alpha 3; catenin alpha-3; Catna3; CTNNA3; RGD1559455; RGD1562230; Vr22
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
216033, 29119, 361839
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q65CL1, Q9UI47
Gene Symbols
CTNNA3
Immunogen
A synthesized peptide derived from human CTNNA3(Accession Q9UI47), corresponding to amino acid residues S502-T552.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CTNNA3
- Catenins are proteins that connect cadherin/beta-catenin cell adhesion complexes to the actin cytoskeleton
- Although originally discovered in testis, alphaT-catenin is expressed in other tissues, the highest levels being observed in heart
- Immunohistochemical analysis showed human alphaTcatenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis
- It is proven that alphaT-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-catenins
- This indicates that this protein is involved in the formation of specific cell-cell contacts in specific types of muscle cells
- The encoded protein has about the same predicted size (100 kDa) as other alpha-catenins to which it shows an overall amino acid identity of 57%
- In cells transfected with alphaT-catenin cDNA, interaction with alpha-catenin was demonstrated by coimmunoprecipitation
- The 892_24D2S antibody against alphaT-catenin does not show any cross reaction with alphaE-catenin or alphaNcatenin in western blot analysis.