GCNT7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106616-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5106616 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GCNT7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GCNT7
Gene Alias
A330041C17Rik; beta 1,6-N-acetylglucosaminyltransferase; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7-like; C20orf105; dJ1153D9.2; gcnt; GCNT7; glucosaminyl (N-acetyl) transferase family member 7; gnt; likely orthologue of H. sapiens chromosome 20 open reading frame 105 (C20orf105); LOC102550196
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
140687, 654821
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q3V3K7, Q6ZNI0
Gene Symbols
GCNT7
Immunogen
A synthesized peptide derived from human GCNT7(Accession Q6ZNI0), corresponding to amino acid residues D324-I374.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total GCNT7
- GCNT7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus
- Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6
- GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion
- Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins
- Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.