PIPA5109454

BRAP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109454-Each-of-1 In Stock ₹ 46,502.50

PIPA5109454 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

BRAP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BRAP

Gene Alias

3010002G07Rik; BRAP; BRAP2; BRCA1 associated protein; BRCA1-associated protein; galectin-2-binding protein; IMP; Impedes mitogenic signal propagation; renal carcinoma antigen NY-REN-63; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; RNF52

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

687346, 72399, 8315

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.21 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

Q7Z569, Q99MP8

Gene Symbols

BRAP

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRAP (NP_006759.3).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MSVSLVVIRL ELAEHSPVPA GFGFSAAAGE MSDEEIKKTT LASAVACLEG KSPGEKVAII HQHLGRREMT DVIIETMKSN PDELKTTVEE RKSSEASPTA QRSKDHSKEC INAAPDSPSK QLPDQISFFS GNPSVEIVHG IMHLYKTNKM TSLKEDVRRS AMLCILTVPA AMTSHDLMKF VAPFNEVIEQ MKIIRDSTPN Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein
  • Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation
  • May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.